| Bioactivity | HIF-2α-IN-1 is a HIF-2α inhibitor has an IC50 of less than 500 nM in HIF-2α scintillation proximity assay.IC50 value: ＜ 500 nMTarget: HIF-2α | ||||||||||||
| Name | HIF-2α-IN-1 | ||||||||||||
| CAS | 1799948-06-3 | ||||||||||||
| Formula | C16H8F5NO4S | ||||||||||||
| Molar Mass | 405.30 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Bruick Richard Keith, et al. HIF-2α inhibitors for treating iron overload disorders. From PCT Int. Appl. (2016), WO 2016057242 A1 20160414. [2]. Dixon Darryl David, et al. Preparation of cyclic sulfone and sulfoximine analogs as HIF-2α inhibitors. From PCT Int. Appl. (2015), WO 2015095048 A1 20150625. |
HIF-2α-IN-1
CAS: 1799948-06-3 F: C16H8F5NO4S W: 405.30
HIF-2α-IN-1 is a HIF-2α inhibitor has an IC50 of less than 500 nM in HIF-2α scintillation proximity assay.IC50 value:
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