Bioactivity | HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM[1]. |
Invitro | HER2-IN-13 (Compound 33) 抑制 hERG 通道,IC50 为 13.3 μM[1]。 |
Name | HER2-IN-13 |
CAS | 2414056-34-9 |
Formula | C26H23ClF2N8O3 |
Molar Mass | 568.96 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ding Zhou, et al. Quinazoline derivatives as antitumor agents. Patent WO2020057511A1. |