| Bioactivity | HECT E3-IN-1 (compound 3) is a HECT E3 ligase inhibitor. HECT E3-IN-1 (compound 3) disrupts Ub binding to the noncovalent Ub-binding site of Nedd4-1[1]. | ||||||||||||
| Name | HECT E3-IN-1 | ||||||||||||
| CAS | 1810058-52-6 | ||||||||||||
| Formula | C21H26N2O4 | ||||||||||||
| Molar Mass | 370.44 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Stefan G Kathman, et al. A Small Molecule That Switches a Ubiquitin Ligase From a Processive to a Distributive Enzymatic Mechanism. J Am Chem Soc. 2015 Oct 7;137(39):12442-5. |
HECT E3-IN-1
CAS: 1810058-52-6 F: C21H26N2O4 W: 370.44
HECT E3-IN-1 (compound 3) is a HECT E3 ligase inhibitor. HECT E3-IN-1 (compound 3) disrupts Ub binding to the noncovalen
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