| Bioactivity | HDAC9-IN-1 (Compound 7g) is a potent HDAC9 inhibitor, with an IC50 of 40 nM. HDAC9-IN-1 significantly inhibits several human cancer cells, induces apoptosis, modulates caspase-related proteins as well as p38, and causes DNA damage[1]. |
| Formula | C27H22N4O3S |
| Molar Mass | 482.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hsu KC, et al. Synthesis and biological evaluation of ortho-phenyl phenylhydroxamic acids containing phenothiazine with improved selectivity for class IIa histone deacetylases. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2406025. |