PeptideDB

DuP-532

CAS: 124750-95-4 F: C23H19F5N6O2 W: 506.43

DuP-532 is an angiotensin type 1 receptor antagonist with potential activity in the suppression of hypertension and hear
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Bioactivity DuP-532 is an angiotensin type 1 receptor antagonist with potential activity in the suppression of hypertension and heart failure. DuP-532 can react with a range of aryl and heteroaryl halides to form perfluoroalkyl(hetero)arenes in moderate to high yields. Computational studies of DuP-532 suggest that coordination of a second phenyl ring ligand may lower the energy barrier for decarboxylation of perfluorocarboxylates, thereby promoting the perfluoroalkylation reaction[1].
CAS 124750-95-4
Formula C23H19F5N6O2
Molar Mass 506.43
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. A class of effective decarboxylative perfluoroalkylating reagents: [(phen)2Cu](O2CRF)