Bioactivity | HDAC-IN-55(8j) is a small molecular compound that can increase the expression of E-cadherin and inhibit the proliferation of cancer cells[1]. |
Invitro | HDAC-IN-55(8j) 作用于SW620 细胞系和 H520 细胞系的 EC50 值分别是 4.47 和 1.61 μM[1]。HDAC-IN-55(8j) (10 μM, 24 h) 可以使 SW620 细胞中的 E-钙粘蛋白表达增加,并抑制 SW620 细胞增殖[1]。 |
Name | HDAC-IN-55 |
CAS | 1268674-16-3 |
Formula | C17H17N3O3 |
Molar Mass | 311.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sydney L Stoops, et al. Identification and optimization of small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells. ACS Chem Biol. 2011 May 20;6(5):452-65. |