| Bioactivity | HBP08 is a selective inhibitor of CXCL12/HMGB1 interaction. HBP08 has a high affinity for HMGB1 (Kd=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration[1]. |
| CAS | 2490442-13-0 |
| Sequence | Gly-Tyr-His-Tyr-Glu-Arg-Trp-Ile-His |
| Shortening | GYHYERWIH |
| Formula | C60H77N17O14 |
| Molar Mass | 1260.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sgrignani J, et al. Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction. J Med Chem. 2021 Sep 23;64(18):13439-13450. |