| Bioactivity | HBC525 is a HBC-like fluorophore and a fluorogenic RNA aptamer (Kd=3.8 nM). HBC525 can be directly used as fusion tags for the imaging and tracking of cellular RNAs of interest. Fluorogenic RNA aptamers have also been used to construct various interesting dynamic RNA nanodevices for cellular target detection and imaging[1][2]. Storage: protect from light. | ||||||||||||
| Target | HBC525: 491/525 nm (Ex/Em) | ||||||||||||
| In Vivo | 荧光RNA适体 | ||||||||||||
| Name | HBC525 | ||||||||||||
| CAS | 2174014-64-1 | ||||||||||||
| Formula | C19H17N3O2 | ||||||||||||
| Molar Mass | 319.36 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Chen X, et al. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs. Nat Biotechnol. 2019;37(11):1287-1293. [2]. Yu Q, et al. Genetically encoded RNA nanodevices for cellular imaging and regulation. Nanoscale. 2021;13(17):7988-8003. |