Bioactivity | H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase. | ||||||||||||
Invitro | It is found that H-HoArg-OH (L-homoarginine), a homologue of arginine, is a strong inhibitor of human bone and liver alkaline phosphatase while it has virtually no effect on intestinal and placental alkaline phosphatases unlike H-HoArg-OH which inhibits intestinal and placental alkaline phosphatases but not the liver and bone enzymes. These four tissues mentioned are the major contributors to the serum alkaline phosphatase[1]. It is also indicated that low levels of the endogenous amino acid H-HoArg-OH are linked to cardiovascular disease[2]. | ||||||||||||
Name | H-HoArg-OH | ||||||||||||
CAS | 156-86-5 | ||||||||||||
Formula | C7H16N4O2 | ||||||||||||
Molar Mass | 188.23 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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