Bioactivity | Glycosidase-IN-1 (Compound 9) is a glycosidase inhibitor synthesized from D-mannose. Glycosidase-IN-1 be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors. Glycosidase-IN-1 has hypoglycemic activity[1]. |
Target | Glycosidase |
Invitro | The synthesis of C5-mono-fluorinated piperidine iminosugar 3a commences with iminosugar Compound 8 that is prepared from D-mannose. In Scheme 2, protection of the ring nitrogen in Compound 8 using Boc-anhydride and Et3N gives Glycosidase-IN-1 (Compound 9)[1]. |
Name | Glycosidase-IN-1 |
CAS | 170376-12-2 |
Formula | C13H23NO5 |
Molar Mass | 273.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Naresh Bhuma, et al. Fluorinated piperidine iminosugars and their N-alkylated derivatives: Synthesis, conformational analysis, immunosuppressive and glycosidase inhibitory activity studies. Tetrahedron 74 (2018) 852-858. |