| Bioactivity | Gly-7-MAD-MDCPT (compound 4b) is an anticancer agent. Gly-7-MAD-MDCPT is a Camptothecin (HY-16560) compound, it shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM[1]. |
| Invitro | Gly-7-MAD-MDCPT (0.1-1000 nM) shows cytotoxic potency to 786-0, BxPC3, HL-60 and SK-MEL-5 with IC50 values of 100-1000 nM[1].Gly-7-MAD-MDCPT (0.1-1000 nM) shows cytotoxic potency to L540cy, MM.1R, M0LM13, Ramos, SK-MEL-5, SU-DHL-4 and U266 with IC50 values of 10-100 nM[1]. |
| Name | Gly-7-MAD-MDCPT |
| CAS | 2378427-68-8 |
| Formula | C24H22N4O7 |
| Molar Mass | 478.45 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Jeffrey Scott, et al. Preparation of camptothecin peptide conjugates as antitumor agents. WO2019195665. 2019 10-10. |
Gly-7-MAD-MDCPT
CAS: 2378427-68-8 F: C24H22N4O7 W: 478.45
Gly-7-MAD-MDCPT (compound 4b) is an anticancer agent. Gly-7-MAD-MDCPT is a Camptothecin (HY-16560) compound, it shows cy
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