Bioactivity | Glutathione arsenoxide (GSAO) is a potential anticancer agent and a tumour metabolism inhibitor. Glutathione arsenoxide targets Mitochondrial endomycin nucleotide transferase (ANT). Glutathione arsenoxide causes cell proliferation arrest and cell death. Glutathione arsenoxide can be used to identify cell-surface proteins, such as Protein disulphide isomerase[1]. |
Target | Mitochondrial endomycin nucleotide transferase (ANT), Protein disulphide isomerase (PDI) |
Name | Glutathione arsenoxide |
CAS | 1271726-51-2 |
Formula | C18H25AsN4O9S |
Molar Mass | 548.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Park D, et al. The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase. Cancer Cell Int. 2012 Mar 26;12(1):11. [2]. Habeck M. Australian scientists design novel antiangiogenic weapon[J]. The Lancet Oncology, 2000, 1(4): 199. |