| Bioactivity | Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. | ||||||||||||
| Invitro | Glucosamine (D-Glucosamine) exhibits dose-dependent DPPH antioxidant activity[2]. Glucosamine treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins[3]. Glucosamine significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells[4]. | ||||||||||||
| Name | Glucosamine | ||||||||||||
| CAS | 3416-24-8 | ||||||||||||
| Formula | C6H13NO5 | ||||||||||||
| Molar Mass | 179.17 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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