Bioactivity | Garlic oil contains various organosulfur compounds with anticancer activities. Garlic oil can significantly activate apoptosis in lung tissue induced by NNK (HY-126477). Furthermore, Garlic oil can markedly reduce NNK-induced DNA damage and prevent the occurrence of lung cancer by inducing the expression of phase II drug-metabolizing enzymes (HO-1, NQO-1, and GSTA1)[1]. |
CAS | 8000-78-0 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhang L, et al. Garlic oil blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis by inducing phase II drug-metabolizing enzymes[J]. Food and Chemical Toxicology, 2021, 157: 112581. |