| Bioactivity | BMP-4 is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. In murine chondrocytes and macrophages, BMP-4 regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 in a dose-dependent manner, effectively suppressing inflammation and alleviating various arthritis symptoms[1]. |
| CAS | 1629625-47-3 |
| Sequence | Arg-Lys-Lys-Asn-Pro-Asn-Cys-Arg-Arg-His |
| Shortening | RKKNPNCRRH |
| Formula | C52H93N25O13S |
| Molar Mass | 1308.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pathade V, et al. Emerging insights of peptide-based nanotherapeutics for effective management of rheumatoid arthritis. Life Sci. 2023 Jan 1;312:121257. |
BMP-4
CAS: 1629625-47-3 F: C52H93N25O13S W: 1308.52
BMP-4 is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. In murine chondro
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.