| Bioactivity | Gamma-Glutamyl Transferase-IN-2 (compound 4dq) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to glutamyltransferase. Gamma-Glutamyl Transferase-IN-2 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation[1]. |
| Target | Gamma-Glutamyl Transferase |
| Name | Gamma-Glutamyl Transferase-IN-2 |
| Formula | C19H13F2N5O2 |
| Molar Mass | 381.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sheng T, et al. Chromatography-Free Synthesis of β-Carboline 1-Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of 尾-Carbolines as Promising Antifungal and Antibacterial Candidates. J Med Chem. 2023 Jul 13;66(13):9040-9056. |