| Bioactivity | Galectin-3/galectin-8-IN-1 (Compound 53) is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values of 4.12 μM and 6.04 μM respectively. Galectin-3/galectin-8-IN-1 inhibits the MRC-5 lung fibroblast cells migration. Galectin-3/galectin-8-IN-1 can be used for research of cancer and tissue fibrosis[1]. |
| Target | Kd: 4.12 μM (Galectin-3) and 6.04 μM (Galectin-8C) |
| Name | Galectin-3/galectin-8-IN-1 |
| Formula | C22H13Cl2N3O4S2 |
| Molar Mass | 518.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Haoming Zhang, et al. Discovery of N-Arylsulfonyl-Indole-2-Carboxamide Derivatives as Galectin-3 and Galectin-8 C-Terminal Domain Inhibitors. ACS Med. Chem. Lett. 2023, 14, 9, 1257-1265. |
Galectin-3/galectin-8-IN-1
CAS: F: C22H13Cl2N3O4S2 W: 518.39
Galectin-3/galectin-8-IN-1 (Compound 53) is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values
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