| Bioactivity | ER degrader 7 (Compound 35t) is an ERα and ERβ degrader. ER degrader 7 inhibits tubulin polymerization. ER degrader 7 inhibits cell viability with IC50s of 0.06, 2.56, 15.84, 1.59, 1.67, 1.37 μM for MCF-7, T47D, MCF-10A, LCC2, T47D D538G, and T47D Y537S cells respectively. ER degrader 7 also inhibits breast cancer tumor growth[1]. |
| Name | ER degrader 7 |
| CAS | 2922929-63-1 |
| Formula | C33H31F4N3O5SSe |
| Molar Mass | 736.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Deng X, et al. Identification of Novel Dual-Target Estrogen Receptor α Degraders with Tubulin Inhibitory Activity for the Treatment of Endocrine-Resistant Breast Cancer. J Med Chem. 2023 Aug 24;66(16):11094-11117. |
ER degrader 7
CAS: 2922929-63-1 F: C33H31F4N3O5SSe W: 736.63
ER degrader 7 (Compound 35t) is an ERα and ERβ degrader. ER degrader 7 inhibits tubulin polymerization. ER degrader 7
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.