Bioactivity | GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents[1]. |
In Vivo | GW438014A (10 mg/kg; i.p.; daily, for 7 d) 抑制大鼠和食物剥夺的遗传性肥胖 ob/ob 小鼠的自发和过夜禁食诱导和 NPY 诱导的摄食[1]。 Animal Model: |
Name | GW438014A |
CAS | 469861-49-2 |
Formula | C23H23N3O4S |
Molar Mass | 437.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Daniels AJ, et, al. Food intake inhibition and reduction in body weight gain in lean and obese rodents treated with GW438014A, a potent and selective NPY-Y5 receptor antagonist. Regul Pept. 2002 Jun 15;106(1-3):47-54. |