Bioactivity | GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively[1]. |
Invitro | GW297361 (20 μM; 15 min) 部分抑制细胞内的 Cdk1[1]。 Western Blot Analysis[1] Cell Line: |
Name | GW297361 |
CAS | 388627-21-2 |
Formula | C16H12N4O3S2 |
Molar Mass | 372.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kung C, et al. Selective kinase inhibition by exploiting differential pathway sensitivity. Chem Biol. 2006 Apr;13(4):399-407. |