Bioactivity | GSK2226649A (compound 2) is a novel activator of satellite cell proliferation and enhanced repair of damaged muscle[1]. |
Invitro | GSK2226649A(compound 2) (0.1-10μM) 可以剂量依赖性促进肌肉干细胞增殖,可有效加速骨骼肌损伤体内小鼠模型中受损骨骼肌的修复[1]。 |
In Vivo | The pharmacokinetic parameters of GSK2226649A(compound 2) in mice Dose(mg) |
Name | GSK2226649A |
CAS | 1848232-20-1 |
Formula | C15H12ClFN6OS |
Molar Mass | 378.81 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Andrew N Billin, et al. Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle. ACS Chem Biol. 2016 Feb 19;11(2):518-29. |