Bioactivity | GRL-1720 is a potent SARS-CoV-2 Mpro inhibitor with an EC50 value of 15 µM. GRL-1720 shows anti-SARS-CoV2 activity[1]. |
Target | EC50: 15 µM (SARS-CoV-2 Mpro) |
Invitro | GRL-1720 (1、10、100 µM;3 天) 显示出对用 100µM SARS-CoV-2WK-521 培养的 VeroE6 细胞的保护活性[1]。 |
Name | GRL-1720 |
CAS | 2835511-03-8 |
Formula | C14H11ClN2O2 |
Molar Mass | 274.70 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hattori SI, et al. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nat Commun. 2021 Jan 28;12(1):668. |