Bioactivity | GR 55562 (dihydrochloride) is a selective 5-HT1B receptor antagonist. GR 55562 can be used for the research of nerve disease[1]. |
In Vivo | GR 55562 (0.1-10 μg/side) 进入伏隔子区域不会引起cocaine杠杆响应[1]。GR 55562 (0.1-10 μg/side)(伏核壳或核中)的未能调节cocaine(5 mg/kg)的辨别作用[1]。GR 55562 (1 μg/side) 显着减弱了对cocaine的辨别作用[1]。 Animal Model: |
Name | GR 55562 dihydrochloride |
CAS | 159533-25-2 |
Formula | C23H27Cl2N3O2 |
Molar Mass | 448.39 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Filip M, et al. Effects of serotonin (5-HT)(1B) receptor ligands, microinjected into accumbens subregions, on cocaine discrimination in rats. Naunyn Schmiedebergs Arch Pharmacol. 2002;366(3):226-234. |