PeptideDB

GR 55562 dihydrochloride

CAS: 159533-25-2 F: C23H27Cl2N3O2 W: 448.39

GR 55562 (dihydrochloride) is a selective 5-HT1B receptor antagonist. GR 55562 can be used for the research of nerve dis
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity GR 55562 (dihydrochloride) is a selective 5-HT1B receptor antagonist. GR 55562 can be used for the research of nerve disease[1].
In Vivo GR 55562 (0.1-10 μg/side) 进入伏隔子区域不会引起cocaine杠杆响应[1]。GR 55562 (0.1-10 μg/side)(伏核壳或核中)的未能调节cocaine(5 mg/kg)的辨别作用[1]。GR 55562 (1 μg/side) 显着减弱了对cocaine的辨别作用[1]。 Animal Model:
Name GR 55562 dihydrochloride
CAS 159533-25-2
Formula C23H27Cl2N3O2
Molar Mass 448.39
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Filip M, et al. Effects of serotonin (5-HT)(1B) receptor ligands, microinjected into accumbens subregions, on cocaine discrimination in rats. Naunyn Schmiedebergs Arch Pharmacol. 2002;366(3):226-234.