Bioactivity | GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK)[1]. |
Target | DLK |
Name | GNE-8505 |
CAS | 1620573-48-9 |
Formula | C21H24F3N5O |
Molar Mass | 419.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Le Pichon CE, et al. Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease. Sci Transl Med. 2017 Aug 16;9(403). pii: eaag0394. |