| Bioactivity | AMPA receptor modulator-1 is a potent, orally active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5)[1]. |
| Target | pIC50: 9.7 (TARP γ-8) |
| Name | AMPA receptor modulator-1 |
| CAS | 2036074-41-4 |
| Formula | C16H11ClF3NO2 |
| Molar Mass | 341.71 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826. |
AMPA receptor modulator-1
CAS: 2036074-41-4 F: C16H11ClF3NO2 W: 341.71
AMPA receptor modulator-1 is a potent, orally active and selective AMPAR regulatory protein TARP γ-8 negative modulator
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