| Bioactivity | Fuberidazole (BAY 33172; Furidazole) is a fungicide. Fuberidazole shows a synergistic effect with cucurbituril (CB) macromolecules, such as CB7 and CB8. Studies have shown that, CB8 induces pKa shifts on Fuberidazole. Fuberidazole significantly inhibits the growth of B. cinerea[1]. | ||||||||||||
| Target | B. cinerea | ||||||||||||
| Invitro | Fuberidazole (FBZ) (10 μM) 在 CB8 (100 μM) 存在的情况下表现出 1.4 个单位的 pKa 偏移[1]。Fuberidazole (10-200 μM; 72 h) 对灰霉病菌 (B. cinerea) 表现出增加的生长抑制率。与 CB7/CB8 结合的 Fuberidazole 对 B. cinerea 的生长至少是 Fuberidazole 单独抑制 3 倍[1]。 | ||||||||||||
| Name | Fuberidazole | ||||||||||||
| CAS | 3878-19-1 | ||||||||||||
| Formula | C11H8N2O | ||||||||||||
| Molar Mass | 184.19 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Saleh N, et al. Enhancement of in vitro fungicidal activity of fuberidazole to Botrytis cinerea by cucurbiturils. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 79: 301-309. |