| Bioactivity | Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, targeting to factor XIa. Frunexian exhibits antithrombotic activity, with no bleeding liability in rat mesenteric arterial puncture model. Frunexian can be used in extracorporeal membrane oxygenation (ECMO) research[1]. |
| Target | IC50: 7 nM (human Factor XIa) |
| Name | Frunexian |
| CAS | 1803270-60-1 |
| Formula | C19H26N4O4 |
| Molar Mass | 374.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pollack CV Jr, et al. EP-7041, a Factor XIa Inhibitor as a Potential Antithrombotic Strategy in Extracorporeal Membrane Oxygenation: A Brief Report. Crit Care Explor. 2020 Sep 15;2(9):e0196. |
Frunexian
CAS: 1803270-60-1 F: C19H26N4O4 W: 374.43
Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, targeting to facto
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