| Bioactivity | Fraxinellone analog 1 (compound 2) is a potent and rapid activator of the Nrf2 mediated antioxidant defense system, which protects against glutamate-mediated excitotoxicity and induces the expression of antioxidant genes Gpx4, Sod1, and Nqo1. Fraxinellone analog 1 has neuroprotective effects and regulatory effects against oxidative stress and inflammation, and can be used in the study of neurodegenerative diseases[1]. |
| Formula | C12H16O3 |
| Molar Mass | 208.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bartman A E, et al. A Novel Analog of the Natural Product Fraxinellone Protects against Endogenous and Exogenous Neurotoxicants[J]. ACS chemical neuroscience, 2024. |