| Bioactivity | Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. | ||||||||||||
| Target | HIV-1 | ||||||||||||
| In Vivo | Fostemsavir (BMS-663068) has good antiviral activity in subjects infected with virus shown to be susceptible (IC50, <100 nM) to the agent[1]. | ||||||||||||
| Name | Fostemsavir | ||||||||||||
| CAS | 864953-29-7 | ||||||||||||
| Formula | C25H26N7O8P | ||||||||||||
| Molar Mass | 583.49 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56(7):3498-507. |
Fostemsavir
CAS: 864953-29-7 F: C25H26N7O8P W: 583.49
Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529.Fostemsavir (BMS-663068) is a novel attachment
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