Bioactivity | Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of prodrug of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist[1]. |
Name | Fmoc-DON-Boc |
CAS | 1998724-98-3 |
Formula | C24H25N3O5 |
Molar Mass | 435.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Rais R, et al. Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma. J Med Chem. 2016 Sep 22;59(18):8621-33. |