Bioactivity | Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells[1]. |
Invitro | Fluorescent polyamine probe-1 is accumulated rapidly in cancer cells (MCF-7), but not in non-tumorigenic cells (MCF-10A)[1].Fluorescent polyamine probe-1 (4 h) shows ten-fold higher uptake efficiency compared with branched probes in MCF-7 cells and the intracellular accumulation can be observed as early as 1 h after probe addition[1]. |
Name | Fluorescent polyamine probe-1 |
CAS | 2678634-03-0 |
Formula | C28H45BF2N8 |
Molar Mass | 542.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Vanhoutte R, et al. Clickable Polyamine Derivatives as Chemical Probes for the Polyamine Transport System. Chembiochem. 2018 May 4;19(9):907-911. |