| Bioactivity | Fibrinogen Binding Inhibitor Peptide is a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen γ-chain carboxy-terminal sequence (γ400-411). Fibrinogen Binding Inhibitor Peptide is a specific binding site of the ligand for activated glycoprotein (GP) IIb/IIIa. | ||||||
| Invitro | Glycoprotein (GP) IIb/IIIa, which exists on the membrane of platelets, changes its form from inactive to active when platelets adhere to collagen exposed on sites of vascular injury. In the circulation, platelet aggregation is mediated by fibrinogen by bridging adjacent platelets through GPIIb/IIIa in an activation-dependent manner. A dodecapeptide HHLGGAKQAGDV (H12), corresponding to the fibrinogen γ-chain carboxy-terminal sequence (γ400-411), is a specific binding site of the ligand for activated GPIIb/IIIa[1]. | ||||||
| Name | Fibrinogen Binding Inhibitor Peptide | ||||||
| CAS | 89105-94-2 | ||||||
| Sequence | His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val | ||||||
| Shortening | HHLGGAKQAGDV | ||||||
| Formula | C50H80N18O16 | ||||||
| Molar Mass | 1189.28 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Fibrinogen Binding Inhibitor Peptide
CAS: 89105-94-2 F: C50H80N18O16 W: 1189.28
Fibrinogen Binding Inhibitor Peptide is a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen γ-chain carboxy-term
Data collection：peptidedb@qq.com
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