| Bioactivity | FXR/CES2 modulator 1 (compound LE-77) is a doul modulator that activates FXR and inhibits CES2. FXR/CES2 modulator 1 effectively mitigates the intestinal toxicity of irinotecan[1]. |
| CAS | 3004676-87-0 |
| Formula | C27H21Cl2NO5 |
| Molar Mass | 510.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhijun Cao, et al. Discovery of the FXR/CES2 dual modulator LE-77 for the treatment of irinotecan-induced delayed diarrhea. Bioorg Chem. 2024 Sep 29:153:107852. |
FXR/CES2 modulator 1
CAS: 3004676-87-0 F: C27H21Cl2NO5 W: 510.37
FXR/CES2 modulator 1 (compound LE-77) is a doul modulator that activates FXR and inhibits CES2. FXR/CES2 modulator 1 eff
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