Bioactivity | FXR agonist 11 (Compound 14) is an FXR agonist with an EC50 of 1.2 μM and a maximum effect of 73.7%. FXR agonist 11 can significantly increase GSH levels in the liver and is used to study drug-induced liver injury diseases[1]. |
CAS | 2768502-17-4 |
Formula | C18H16N2O5 |
Molar Mass | 340.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Qianqian Qiu, et al. Design, synthesis, and biological evaluation of novel FXR agonists based on auraptene. Bioorg Chem. 2021 Oct:115:105198. |