| Bioactivity | FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM[1]. |
| Target | IC50: (ACAT) |
| Invitro | FR-190809 inhibits foam cell formation with an IC50 of 215 nM[1]. |
| Name | FR-190809 |
| CAS | 215589-63-2 |
| Formula | C29H34FN3O6S2 |
| Molar Mass | 603.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tanaka A, et al. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 3. Discovery of a novel series of N-alkyl-N-[(fluorophenoxy)benzyl]-N'-arylureas with weak toxicological effects on adrenal glands. J Med Chem. 1998 Oct 22;41(22):4408-20. |
FR-190809
CAS: 215589-63-2 F: C29H34FN3O6S2 W: 603.73
FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with
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