| Bioactivity | FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1]. |
| Invitro | FGFR3-IN-5 (compound 37; 5 mM; 1 h; HEK-293 细胞) 抑制 FGFR 磷酸化，对 FGFR3 和 FGFR1 的 IC50 值分别为8 nM 和 59 nM[1]。 |
| Name | FGFR3-IN-5 |
| CAS | 2446664-72-6 |
| Formula | C24H24FN7O3 |
| Molar Mass | 477.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. James FB, et, al. Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases. WO2020131627. |
FGFR3-IN-5
CAS: 2446664-72-6 F: C24H24FN7O3 W: 477.49
FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1,
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.