| Bioactivity | FGFR1 inhibitor-10 (Compound 4i) is an FGFR1 inhibitor (IC50: 28 nM). FGFR1 inhibitor-10 inhibits the phosphorylation of FGFR1. FGFR1 inhibitor-10 has anti-angiogenic, anti-invasion activity, and anti-tumor effect[1]. |
| Name | FGFR1 inhibitor-10 |
| CAS | 2426769-76-6 |
| Formula | C26H30F3N7O2S |
| Molar Mass | 561.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li YL, et al. Design, synthesis and evaluation of novel pyrimidinylaminothiophene derivatives as FGFR1 inhibitors against human glioblastoma multiforme. Eur J Med Chem. 2023 Nov 15;260:115764. |
FGFR1 inhibitor-10
CAS: 2426769-76-6 F: C26H30F3N7O2S W: 561.62
FGFR1 inhibitor-10 (Compound 4i) is an FGFR1 inhibitor (IC50: 28 nM). FGFR1 inhibitor-10 inhibits the phosphorylation of
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