PeptideDB

EGFR-IN-88

CAS: 2944452-34-8 F: C22H18Cl2N4O2S W: 473.37

EGFR-IN-88 (Compound 4i) is an EGFR inhibitor (IC50: 87 nM). EGFR-IN-88 shows cytotoxicity against A549 cell with an IC5
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Bioactivity EGFR-IN-88 (Compound 4i) is an EGFR inhibitor (IC50: 87 nM). EGFR-IN-88 shows cytotoxicity against A549 cell with an IC50? of 3.902? μM. EGFR-IN-88 can induce cell apoptosis[1].
Target 87 nM (EGFR)
Name EGFR-IN-88
CAS 2944452-34-8
Formula C22H18Cl2N4O2S
Molar Mass 473.37
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Ali SH, et al. Design, synthesis, and molecular docking studies of novel quinoxaline derivatives as anticancer agents. Chem Biol Drug Des. 2023 Aug;102(2):303-315.