| Bioactivity | FEN1-IN-1 (compound 1) is a flap endonuclease 1 (FEN1) inhibitor. FEN1-IN-1 binds to the active site of FEN1 and partly achieves inhibition by the co-ordination of Mg2+ ions[1]. | ||||||||||||
| Target | FEN1 | ||||||||||||
| Name | FEN1-IN-1 | ||||||||||||
| CAS | 824983-91-7 | ||||||||||||
| Formula | C15H12N2O5S | ||||||||||||
| Molar Mass | 332.33 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Ward TA, et al. Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes. PLoS One. 2017 Jun 19;12(6):e0179278. |
FEN1-IN-1
CAS: 824983-91-7 F: C15H12N2O5S W: 332.33
FEN1-IN-1 (compound 1) is a flap endonuclease 1 (FEN1) inhibitor. FEN1-IN-1 binds to the active site of FEN1 and partly
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