| Bioactivity | FABP4-IN-4 (Compound 30) is an orally active inhibitor for FABP, with IC50 of 1.18 μM for FABP 1. FABP4-IN-4 improves the glucose tolerance, reduces the level of blood glucose, plasma lipids and hepatic inflammatory factors, attenuates hepatic steatosis, and exhibits anti-inflammatory effects in mouse diet-induced obesity models[1]. |
| Target | IC50: 1.18 μM (FABP 1) |
| Formula | C25H23N3O5S2 |
| Molar Mass | 509.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen L, et al., Design, synthesis, and biological evaluation of novel highly selective non-carboxylic acid FABP1 inhibitors. Eur J Med Chem. 2024 Jul 22;276:116705. |