| Bioactivity | F16 is a potent growth inhibitor of the neu-overexpressing cells and also selectively inhibits proliferation of mammary epithelial as well as a variety of mouse mammary tumor and human breast cancer cell lines. F16 is a mitochondriotoxic compound, and triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell[1][2]. |
| Invitro | F16 (3 μM; 3 days/7 days) affects growth in several mouse and human cancer cell lines[1].F16 arrests cell cycle and increases apoptosis in F16-sensitive EpH4-A6 cells[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | F16 |
| CAS | 36098-33-6 |
| Formula | C16H15IN2 |
| Molar Mass | 362.21 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |