| Bioactivity | Etavopivat is a potent, selective, orally bioavailable red blood cell (RBC) pyruvate kinase (PKR) activator. Etavopivat has potent antisickling effects[1]. | ||||||||||||
| Name | Etavopivat | ||||||||||||
| CAS | 2245053-57-8 | ||||||||||||
| Formula | C22H23N3O6S | ||||||||||||
| Molar Mass | 457.50 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Shrestha A, et al. FT-4202, an oral PKR activator, has potent antisickling effects and improves RBC survival and Hb levels in SCA mice. Blood Adv. 2021 May 11;5(9):2385-2390. |