Bioactivity | Esmolol acid (ASL-8123) hydrochloride is a weak β-adrenoceptor antagonist. Esmolol acid hydrochloride dose-dependently inhibits the heart rate and diastolic pressure responses to isoproterenol and can be used in renal failure studies[1][2]. |
CAS | 83356-60-9 |
Formula | C15H24ClNO4 |
Molar Mass | 317.81 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. J E Shaffer, et al. Beta-adrenoreceptor antagonist potency and pharmacodynamics of ASL-8123, the primary acid metabolite of esmolol. J Cardiovasc Pharmacol. 1988 Feb;11(2):187-92. [2]. J F Flaherty, et al. Pharmacokinetics of esmolol and ASL-8123 in renal failure. Clin Pharmacol Ther. 1989 Mar;45(3):321-7. |