| Bioactivity | CHDI-00484077 (Compound 12) is a CNS-penetrant class IIa HDAC inhibitor, with IC50s of 0.01 μM (HDAC4), 0.02 μM(HDAC5), 0.02 μM (HDAC7), 0.03 μM (HDAC9) respectively. CHDI-00484077 can be used for research of huntington’s disease[1]. |
| CAS | 3025894-92-9 |
| Formula | C18H21F3N4O2 |
| Molar Mass | 382.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Stott AJ, et al. Evaluation of 5-(Trifluoromethyl)-1,2,4-oxadiazole-Based Class IIa HDAC Inhibitors for Huntington's Disease. ACS Med Chem Lett. 2021 Feb 11;12(3):380-388. |
CHDI-00484077
CAS: 3025894-92-9 F: C18H21F3N4O2 W: 382.38
CHDI-00484077 (Compound 12) is a CNS-penetrant class IIa HDAC inhibitor, with IC50s of 0.01 μM (HDAC4), 0.02 μM(HDAC5)
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This product is for research use only, not for human use. We do not sell to patients.