| Bioactivity | Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta[1].Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models[2], has selective inhibitory activity towards cyclooxygenase-2 (COX-2)[1].Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways[3]. | |||||||||
| Invitro | Esculentoside A (0-10 μM; 24 hours) reduced the release of TNF concentration in primed macrophages [4]. | |||||||||
| Name | Esculentoside A | |||||||||
| CAS | 65497-07-6 | |||||||||
| Formula | C42H66O16 | |||||||||
| Molar Mass | 826.96 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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