PeptideDB

Esculentoside A

CAS: 65497-07-6 F: C42H66O16 W: 826.96

Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta.Esculentoside A (EsA) po
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Bioactivity Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta[1].Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models[2], has selective inhibitory activity towards cyclooxygenase-2 (COX-2)[1].Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways[3].
Invitro Esculentoside A (0-10 μM; 24 hours) reduced the release of TNF concentration in primed macrophages [4].
Name Esculentoside A
CAS 65497-07-6
Formula C42H66O16
Molar Mass 826.96
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month