| Bioactivity | Erasin is a potent Erlotinib (HY-50896)-resistance antagonizing STAT3 inhibitor with IC50s of 9.7 and 24 μM against STAT3 and STAT1, respectively. Erasin induces cancer cells apoptosis[1]. |
| Invitro | Erasin 抑制 STAT SH2 结构域介导的蛋白-蛋白相互作用[1]。Erasin (0-80 μM;24 h) 诱导 MDA-MB-231、HCC-827 和 Erlotinib (HY-50896) 耐药 HCC-827 细胞凋亡[1]。 Western Blot Analysis[1] Cell Line: |
| Name | Erasin |
| Formula | C20H19N3O3 |
| Molar Mass | 349.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |