| Bioactivity | Eprinomectin-d3 (MK-397-d3) is the deuterium-labeled Eprinomectin (HY-12643)[1]. Eprinomectin is an avermectin for use as a topical endectocide for cattle[2]. |
| Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 |
| Name | Eprinomectin-d3 |
| Formula | C49H70D3NO14 |
| Molar Mass | 903.12 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Shoop WL, et al. Eprinomectin: a novel avermectin for use as a topical endectocide for cattle. Int J Parasitol. |