Bioactivity | Dimethyldithiocarbamate-d6 sodium dihydrate is the deuterium-labeled Dimethyldithiocarbamate (HY-W098697)[1]. Ferric dimethyl‐dithiocarbamate (ferbam) exhibits oral toxicity in rodents[2]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 |
Name | Dimethyldithiocarbamate-d6 sodium dihydrate |
Formula | C3H4D6NNaO2S2 |
Molar Mass | 185.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Lee CC, et al. Oral toxicity of ferric dimethyl-dithiocarbamate (ferbam) and tetramethylthiuram disulfide (thiram) in rodents. J Toxicol Environ Health. 1978 Jan;4(1):93-106. |