| Bioactivity | Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC50 of 1.45 nM. Epostane blocks ovulation and pregnancy in rats[1]. |
| In Vivo | Epostane (0-200 mg/kg，口服，单剂量) 抑制成熟大鼠的排卵和促性腺激素刺激的未成熟大鼠的排卵，通过降低血浆黄体酮水平来终止妊娠[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 80471-63-2 |
| Formula | C22H31NO3 |
| Molar Mass | 357.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Snyder BW, et al., Inhibition of ovulation in rats with epostane, an inhibitor of 3 beta-hydroxysteroid dehydrogenase. Proc Soc Exp Biol Med. 1984 Jul;176(3):238-42. |