Ep300/CREBBP-IN-4_product_DataBase

CAS: 2259641-42-2 F: C23H22F3N5O3 W: 473.45

Ep300/CREBBP-IN-4 (Example 56) is a potent Ep300 and CREBBP inhibitor with IC50s of 0.024 and 0.064 μM, respectively. E

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	Ep300/CREBBP-IN-4 (Example 56) is a potent Ep300 and CREBBP inhibitor with IC50s of 0.024 and 0.064 μM, respectively. Ep300/CREBBP-IN-4 can be used for the research of cancer[1].
Invitro	Ep300/CREBBP-IN-4 (Example 56) 抑制细胞内 H3K27Ac 活性，其 IC50 为 0.020 μM[1]。Ep300/CREBBP-IN-4 (38 nM-10 mM; 3 days) 抑制 LK2 和 TE-8 细胞生长，GI50 分别为 98.803 μM 和 88.333 μM [1]。 Cell Viability Assay[1] Cell Line:
Name	Ep300/CREBBP-IN-4
CAS	2259641-42-2
Formula	C23H22F3N5O3
Molar Mass	473.45
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. NAITO Hiroyuki, et al. EP300 / CREBBP inhibitor. Patent JPWO2018235966A1.

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